Product Name	Anti-HDC/AF555
Chinese Name	AF555标记的L-组氨酸脱羧酶抗体
Alias	L-Histidine decarboxylase; EC 4.1.1.22; HDC; L-HDC; Histidine decarboxylase; DCHS_HUMAN.
Research Area	immunology  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	74kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HDC
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Histidine decarboxylase(HDC) is the enzyme that calalyses the conversion of histidine into histamine. It can be found in the histamine secreting ECL cells of some species, as well as in the mast cells.The biogenic amine histamine is an important modulator of numerous physiological processes, including neurotransmission, gastric acid secretion and smooth muscle tone. Function: Catalyzes the biosynthesis of histamine from histidine. Subunit: Homodimer. Similarity: Belongs to the group II decarboxylase family. Database links: Entrez Gene: 3067 Human Entrez Gene: 15186 Mouse Entrez Gene: 24443 Rat Omim: 142704 Human SwissProt: P19113 Human SwissProt: P23738 Mouse SwissProt: P16453 Rat Unigene: 1481 Human Unigene: 18603 Mouse Unigene: 48653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 主要用于多种变态反应及炎性浸润改变有关的研究。

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