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Rabbit Anti-SYTL5/AF555 Conjugated antibody
Rabbit Anti-SYTL5/AF555 Conjugated antibody
synaptotagmin-like protein 5 isoform 2; synaptotagmin-like protein 5; SYTL5 protein; synaptotagmin-like 5; ENSMUSG00000054453; slp5; SYTL5.
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  • NO.:SL4145R-AF555
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-SYTL5/AF555
Chinese Name AF555标记的突触样蛋白5亚型2抗体
Alias synaptotagmin-like protein 5 isoform 2; synaptotagmin-like protein 5; SYTL5 protein; synaptotagmin-like 5; ENSMUSG00000054453; slp5; SYTL5.  
Research Area immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 81kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SYTL5
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Function:
May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in placenta and liver.

Similarity:
Contains 2 C2 domains.
Contains 1 FYVE-type zinc finger.
Contains 1 RabBD (Rab-binding) domain.

Database links:

Entrez Gene: 94122 Human

Entrez Gene: 236643 Mouse

Entrez Gene: 302538 Rat

SwissProt: Q8TDW5 Human

SwissProt: Q80T23 Mouse

SwissProt: Q812E4 Rat

Unigene: 662334 Human

Unigene: 246606 Mouse

Unigene: 92480 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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