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Rabbit Anti-KAT9/AF488 Conjugated antibody
Rabbit Anti-KAT9/AF488 Conjugated antibody
DKFZp761L098; Elongation protein 3 homolog (S. cerevisiae); Elongation protein 3 homolog; ELONGATION PROTEIN 3, S. CEREVISIAE, HOMOLOG OF; elongator acetyltransferase complex subunit 3; Elongator complex protein 3; Elongator complex protein 3; elp3; ELP3_
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  • NO.:SL20539R-AF488
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Dog,Pig,Cow,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-KAT9/AF488
Chinese Name AF488标记的组蛋白乙酰转移酶KAT9抗体
Alias DKFZp761L098; Elongation protein 3 homolog (S. cerevisiae); Elongation protein 3 homolog; ELONGATION PROTEIN 3, S. CEREVISIAE, HOMOLOG OF; elongator acetyltransferase complex subunit 3; Elongator complex protein 3; Elongator complex protein 3; elp3; ELP3_HUMAN; FLJ10422; hELP3; Hypothetical protein DKFZp761L098; Kat9.  
Research Area Cell biology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Dog, Pig, Cow, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 62kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human KAT9
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Function:
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ELP3 family.
Contains 1 N-acetyltransferase domain.

Database links:

Entrez Gene: 55140 Human

Entrez Gene: 74195 Mouse

Omim: 612722 Human

SwissProt: Q9H9T3 Human

SwissProt: Q9CZX0 Mouse

Unigene: 491336 Human

Unigene: 29719 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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