Product Name	Anti-RANBP17/AF488
Chinese Name	AF488标记的RANBinding protein17抗体
Alias	Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7.
Research Area	Cell biology  Signal transduction  Binding protein  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Chimpanzee, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	124kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RANBP17
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002] Function: May function as a nuclear transport receptor. Subcellular Location: Cytoplasm. Nucleus. Nucleus > nuclear pore complex. Tissue Specificity: Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. Similarity: Belongs to the exportin family. Database links: Entrez Gene: 739299 Chimpanzee Entrez Gene: 529222 Cow Entrez Gene: 479293 Dog Entrez Gene: 64901 Human Entrez Gene: 100526145 Pig Entrez Gene: 303029 Rat Omim: 606141 Human SwissProt: Q9H2T7 Human Unigene: 410810 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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