Product Name	Anti-GLYAT/AF488
Chinese Name	AF488标记的甘胺酸-N-酰基转移酶抗体
Alias	AAc; ACGNAT; Acyl CoA:glycine N acyltransferase; Acyl-CoA:glycine N-acyltransferase; Aralkyl acyl CoA N acyltransferase; Aralkyl acyl CoA N acyltransferase; Aralkyl acyl CoA:amino acid N acyltransferase; Aralkyl acyl CoA:amino acid N acyltransferase; Aralkyl acyl-CoA N-acyltransferase; Aralkyl acyl-CoA:amino acid N-acyltransferase; Aralkyl CoA N acyltransferase; CAT; GAT; GLYAT; GLYAT_HUMAN; Glycine N acyltransferase; Glycine N acyltransferase; Glycine N-acyltransferase; HRP 1(CLP); HRP-1(CLP); HRP1(CLP); OTTHUMP00000235930; OTTHUMP00000235931; OTTHUMP00000235932.
Research Area	Tumour  Cell biology  Signal transduction  Stem cells  The new supersedes the old  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	34kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GLYAT
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines. Subcellular Location: Mitochondrion. Tissue Specificity: Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. Similarity: Belongs to the glycine N-acyltransferase family. Database links: Entrez Gene: 281787 Cow Entrez Gene: 483463 Dog Entrez Gene: 10249 Human Entrez Gene: 107146 Mouse Entrez Gene: 293779 Rat Omim: 607424 Human SwissProt: Q6IB77 Human SwissProt: Q91XE0 Mouse SwissProt: Q5PQT3 Rat Unigene: 145384 Human Unigene: 39974 Mouse Unigene: 21872 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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