Product Name	Anti-LIMKAIN B1/AF488
Chinese Name	AF488标记的减数分裂阻滞蛋白1抗体
Alias	KIAA0430; Limkain-b1; LKAP; MARF1_HUMAN; MARF1; Meiosis arrest female 1; Meiosis arrest female protein 1; PPP1R34; Protein phosphatase 1, regulatory subunit 34.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	193kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LIMKAIN B1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010] Function: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity). Subunit: Interacts with LIMK2. Subcellular Location: Peroxisome. Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 9665 Human Entrez Gene: 223989 Mouse Omim: 614593 Human SwissProt: Q9Y4F3 Human SwissProt: Q8BJ34 Mouse Unigene: 173524 Human Unigene: 85442 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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