Product Name	Anti-SPEF1/AF488
Chinese Name	AF488标记的精子鞭毛蛋白1抗体
Alias	C20orf28; Calponin homology and microtubule associated protein; CLAMP; SPEF1A; Sperm flagellar 1; Sperm flagellar protein 1.
Research Area	Cell biology  immunology  Developmental biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Pig, Cow, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	27kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPEF1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: CLAMP is a 236 amino acid protein that is present in epididymal sperm and localizes to the cell projection, as well as to the cytoplasm. Expressed in lung, brain and testis, CLAMP functions as a microtubule-associated protein that is thought to play a role in microtubule bundling. Human CLAMP exists as two alternatively spliced isoforms and shares a high degree of homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding CLAMP maps to human chromosome 20, which houses over 600 genes and comprises nearly 2% of the human genome. Subcellular Location: Cytoplasm. Cell projection; cilium; flagellum. Cytoplasm; cytoskeleton; cilium axoneme. Note: Present in the tails of developing and epididymal sperm, internal to the fibrous sheath and around the outer dense fibers of the sperm flagellum. Also found at the apical tip of cilia. Database links: Entrez Gene: 25876 Human Omim: 610674 Human SwissProt: Q9Y4P9 Human Unigene: 72620 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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