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Rabbit Anti-TOMM40/AF488 Conjugated antibody
Rabbit Anti-TOMM40/AF488 Conjugated antibody
C19orf1; D19S1177E; Haymaker protein; Mitochondrial import receptor subunit TOM40 homolog; Mitochondrial outer membrane protein; Mitochondrial outer membrane protein TOM40; p38.5; PER EC1; PEREC1; Probable mitochondrial import receptor subunit TOM40 homol
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  • NO.:SL17227R-AF488
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,Xenopus laevis)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-TOMM40/AF488
Chinese Name AF488标记的TOMM40蛋白抗体
Alias C19orf1; D19S1177E; Haymaker protein; Mitochondrial import receptor subunit TOM40 homolog; Mitochondrial outer membrane protein; Mitochondrial outer membrane protein TOM40; p38.5; PER EC1; PEREC1; Probable mitochondrial import receptor subunit TOM40 homolog; Protein Haymaker; TOM40; TOM40_HUMAN; TOMM40; Translocase of outer membrane 40 kDa subunit homolog; Translocase of outer mitochondrial membrane 40; Translocase of outer mitochondrial membrane 40 homolog (yeast); Translocase of outer mitochondrial membrane 40 homolog.  
Research Area Cell biology  Signal transduction  Transporter  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Xenopus laevis)
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 37kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TOMM40
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria (Humphries et al., 2005 [PubMed 15644312]).[supplied by OMIM, May 2008]

Function:
Channel-forming protein essential for import of protein precursors into mitochondria.

Subunit:
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with mitochondrial targeting sequences.

Subcellular Location:
Mitochondrion outer membrane.

Similarity:
Belongs to the Tom40 family.

Database links:

Entrez Gene: 10452 Human

Entrez Gene: 510219 Cow

Entrez Gene: 611055 Dog

Entrez Gene: 53333 Mouse

Entrez Gene: 308416 Rat

Entrez Gene: 380301 Xenopus laevis

Omim: 608061 Human

SwissProt: Q1LZB5 Cow

SwissProt: O96008 Human

SwissProt: Q9QYA2 Mouse

SwissProt: Q75Q40 Rat

SwissProt: Q7ZTM6 Xenopus laevis

Unigene: 655909 Human

Unigene: 416870 Mouse

Unigene: 440173 Mouse

Unigene: 17999 Rat

Unigene: 7913 Xenopus laevis



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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