Product Name	Anti-INO80D/AF488
Chinese Name	AF488标记的INO80D蛋白抗体
Alias	FLJ20309; IN80D_HUMAN; INO80 complex subunit D; OTTHUMP00000206351.
Research Area	Cell biology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	98kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human INO80D
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The INO80 complex contributes to a wide variety of chromatin-dependent nuclear transactions, including transcription, DNA repair and DNA replication. Evolutionarily conserved from yeast to human, theINO80 complex belongs to a subfamily of the ATP-dependent chromatin remodelers and is characterized by a split ATPase domain in the core ATPase subunit. ATP-dependent chromatin remodeling complexes contain ATPases of the Swi/Snf superfamily and alter DNA accessibility of chromatin in an ATP-dependent manner. INO80D (INO80 complex subunit D), is an 878 amino acid protein that is a component of the chromatin-remodeling INO80 complex. Function: This protein is a component of the chromatin-remodeling INO80 complex, which is at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E. Subunit: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80. {ECO:0000269|PubMed:16230350, ECO:0000269|PubMed:18922472, ECO:0000269|PubMed:21303910}. Similarity: Belongs to the INO80D family. {ECO:0000305}. Database links: Entrez Gene: 54891 Human Entrez Gene: 227195 Mouse SwissProt: Q53TQ3 Human SwissProt: Q66JY2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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