Product Name	Anti-DSCR3/AF488
Chinese Name	AF488标记的唐氏综合征临界区域蛋白3抗体
Alias	Down syndrome critical region protein 3; Down syndrome critical region protein A; Dscr3; DSCR3_HUMAN.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	33kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DSCR3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008] Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the VPS26 family. Database links: Entrez Gene: 10311 Human Omim: 605298 Human SwissProt: O14972 Human Unigene: 369488 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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