Product Name	Anti-GLYCTK/AF488
Chinese Name	AF488标记的HBeAgBinding protein4/甘油激酶抗体
Alias	HBEBP2; CG9886 like; GLCTK_HUMAN; Glycerate kinase; Glyctk; GLYCTK; HBeAg binding protein 2; HBeAg binding protein 4; HBeAg-binding protein 4; HBeAgBP4A; HBEBP2; HBEBP4.
Research Area	Cell biology  Neurobiology  Signal transduction  Stem cells  Bacteria and viruses  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	55kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HBEBP2/GLYCTK
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] Subcellular Location: Cytoplasm and Cytoplasm. Mitochondrion. Tissue Specificity: Widely expressed. DISEASE: Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA) [MIM:220120]. D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Similarity: Belongs to the glycerate kinase type-2 family. Database links: Entrez Gene: 132158 Human Entrez Gene: 235582 Mouse Entrez Gene: 684314 Rat Omim: 610516 Human SwissProt: Q9BE01 Cynomolgus Monkey SwissProt: Q8IVS8 Human SwissProt: Q8QZY2 Mouse SwissProt: Q0VGK3 Rat Unigene: 415312 Human Unigene: 335420 Mouse Unigene: 202605 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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