Product Name	Anti-DCBLD2/AF488
Chinese Name	AF488标记的endothelial cells和平滑肌细胞衍生的神经纤毛蛋白抗体
Alias	CLCP1; coagulation factor V/VIII-homology domains protein 1; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; discoidin CUB and LCCL domain containing 2; Discoidin, CUB and LCCL domain-containing protein 2; endothelial and smooth muscle cell-derived neuropilin-like protein; ESDN; DCBD2_HUMAN.
Research Area	Tumour  Cell biology  immunology  Cell adhesion molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	78kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DCBLD2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells. Similarity: Contains 1 CUB domain. Contains 1 F5/8 type C domain. Contains 1 LCCL domain. Database links: Entrez Gene: 131566 Human Entrez Gene: 73379 Mouse Entrez Gene: 155696 Rat Omim: 608698 Human SwissProt: Q96PD2 Human SwissProt: Q91ZV3 Mouse SwissProt: Q91ZV2 Rat Unigene: 203691 Human Unigene: 373589 Mouse Unigene: 157411 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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