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Rabbit Anti-STMN3/AF488 Conjugated antibody
Rabbit Anti-STMN3/AF488 Conjugated antibody
Sclip; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Stathmin like 3; STMN3_HUMAN.
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  • NO.:SL6596R-AF488
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Cow,Horse,Sheep,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-STMN3/AF488
Chinese Name AF488标记的原癌基因18家族STMN3蛋白抗体
Alias Sclip; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Stathmin like 3; STMN3_HUMAN.  
Research Area Cell biology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 21kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human STMN3
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
STMN3 belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.

Function:
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity).

Subunit:
Interacts with STAT3 (By similarity).

Subcellular Location:
Golgi apparatus. Cell projection, growth cone. Cell projection, axon.

Tissue Specificity:
Neuron specific.

Post-translational modifications:
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.

Similarity:
Belongs to the stathmin family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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