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Product Name Anti-THRSP/AF488 Chinese Name AF488标记的甲状腺激素反应蛋白抗体 Alias Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein; Thyroid hormone responsive SPOT14; Thyroid hormone-inducible hepatic protein. Research Area Tumour Cell biology Signal transduction TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 17kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human THRSP Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides.
Function:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
Subunit:
Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1.
Subcellular Location:
Cytoplasm.Nucleus.
Tissue Specificity:
Mainly expressed in tissues that synthesize triglycerides.
Similarity:
Mainly expressed in tissues that synthesize triglycerides.
Belongs to the SPOT14 family.
Database links:Entrez Gene: 7069 Human
Entrez Gene: 21835 Mouse
Omim: 601926 Human
SwissProt: Q92748 Human
SwissProt: Q62264 Mouse
Unigene: 591969 Human
Unigene: 28585 Mouse
Unigene: 81140 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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