Product Name	Anti-SLC6A18/AF350
Chinese Name	AF350标记的溶质载体家族6成员18抗体
Alias	S6A18_HUMAN; Sodium-dependent neutral amino acid transporter B(0)AT3; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3.
Research Area	Cell biology  immunology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	71kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC6A18
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	Function: Functions as a sodium and chloride-dependent neutral amino acid transporter. {ECO:0000250}. Subunit: Associates with TMEM27. TMEM27 association is required for functional expression in kidney. {ECO:0000250}. Subcellular Location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Tissue Specificity: Abundantly expressed in kidney, but not in intestine. {ECO:0000269|PubMed:15286787}. DISEASE: Note=Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20. Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily. {ECO:0000305}. Database links: Entrez Gene: 348932 Human Entrez Gene: 22598 Mouse Entrez Gene: 29323 Rat Omim: 610300 Human SwissProt: Q96N87 Human SwissProt: O88576 Mouse SwissProt: Q62687 Rat Unigene: 213284 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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