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Rabbit Anti-Rsafd1/AF350 Conjugated antibody
Rabbit Anti-Rsafd1/AF350 Conjugated antibody
FLJ10900; GC23001; MGC60291; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; RSAFD1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW-synthesizing protein; TYW1; TYW1_HUMAN; TYW1A; YPL207W.
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  • NO.:SL18864R-AF350
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-Rsafd1/AF350
Chinese Name AF350标记的Rsafd1蛋白抗体
Alias FLJ10900; GC23001; MGC60291; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; RSAFD1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW-synthesizing protein; TYW1; TYW1_HUMAN; TYW1A; YPL207W.  
Research Area Cell biology  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 84kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Rsafd1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]

Function:
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

Similarity:
Belongs to the TYW1 family.
Contains 1 flavodoxin-like domain.

Database links:

Entrez Gene: 55253 Human

Entrez Gene: 100929 Mouse

Entrez Gene: 304423 Rat

Omim: 611243 Human

SwissProt: Q9NV66 Human

SwissProt: Q8BJM7 Mouse

Unigene: 520917 Human

Unigene: 271296 Mouse

Unigene: 163211 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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