Product Name	Anti-MCPT4/AF350
Chinese Name	AF350标记的肥大细胞蛋白酶4抗体
Alias	Mast cell protease 4; Mcp 4; Mcpt4; MCPT4_MOUSE; MMCP 4; MMCP 4A; MMCP 4B; MMCP-4; MMCP4; MMCP4A; MMCP4B; MSMCP; Myonase; Serosal mast cell protease.
Research Area	Cell biology  immunology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Mouse, Rat, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	25kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse MCPT4
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	Function: Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4- -Ile-5' bond of angiotensin I and the 'Phe-20- -Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8- -His-9' bond of angiotensin I and the 'Phe-4- -Ala-5' and 'Tyr-10- -Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Tissue Specificity: Submucosal mast cells. In femoral muscle, detected in myocytes but not in mast cells. Similarity: Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain. Database links: Entrez Gene: 17227 Mouse SwissProt: P21812 Mouse Unigene: 439684 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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