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Rabbit Anti-Leishmania Major Surface Protease/AF350 Conjugated antibody
Rabbit Anti-Leishmania Major Surface Protease/AF350 Conjugated antibody
Cell surface protease; gp63; Leishmanolysin; Major surface glycoprotein; Major surface protease; MSP; GP63_LEIMA; Promastigote surface endopeptidase; Protein gp63; PSP.
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Product Name Anti-Leishmania Major Surface Protease/AF350
Chinese Name AF350标记的利什曼原虫表面蛋白酶抗体
Alias Cell surface protease; gp63; Leishmanolysin; Major surface glycoprotein; Major surface protease; MSP; GP63_LEIMA; Promastigote surface endopeptidase; Protein gp63; PSP.  
Research Area immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 51kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from Leishmania Major Surface Protease
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The major surface metalloproteinase Gp63 plays an important role in the initial stages of Leishmania/macrophage interactions and the intracellular survival of the parasite. Leishmania is a protozoan of the genus of trypanosome, and the parasite responsible for the disease leishmaniasis.

Subcellular Location:
Cell Membrane

Post-translational modifications:
The phosphatidylinositol moiety of the GPI-anchor contains a fully saturated, unbranched 1-O-alkyl chain (mainly C24:0) and a mixture of fully saturated unbranched 2-O-acyl chains

Similarity:
Belongs to the peptidase M8 family.

Database links:

Entrez Gene: 5653263 Leishmania major

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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