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Rabbit Anti-PLTP/AF350 Conjugated antibody
Rabbit Anti-PLTP/AF350 Conjugated antibody
HDLCQ9; High density lipoprotein cholesterol level quantitative trait locus 9, included; Lipid transfer protein II; OD107; Phospholipid transfer protein; Plasma phospholipid transfer protein; PLTP_HUMAN.
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Details

Product Name Anti-PLTP/AF350
Chinese Name AF350标记的磷脂转移蛋白抗体
Alias HDLCQ9; High density lipoprotein cholesterol level quantitative trait locus 9, included; Lipid transfer protein II; OD107; Phospholipid transfer protein; Plasma phospholipid transfer protein; PLTP_HUMAN.  
Research Area Tumour  Cell biology  immunology  transcriptional regulatory factor  The cell membrane受体  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 53kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PLTP C-terminus
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Function:
Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.

Subcellular Location:
Secreted.

Tissue Specificity:
Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.

Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Database links:
UniProtKB/Swiss-Prot: P55058.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Partial purchase records(bought amounts latest6)

UsernameQuantitybought time
Et***12024-07-18
Fr***22024-05-09
Fi***22024-04-21
Ta***12023-12-24
Fr***12023-06-10
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