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Cytochalasin E
Product introduction
Cytorelaxin is a fungal metabolite that inhibits actin polymerization through cells.
Molecular formula: C28H33NO7, molecular weight: 495.56
Physical properties and indexes:
Appearance: …………………… White crystalline powder
Melting point: …………………… 205 ~ 210 ° C
Solubility: ………………… Soluble in DMSO(10mg/ml), ethanol (2mg/ml)
Burning residue: ……………… < 0.1%
Purity: …………………… > 98%
Biological activity:
The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B which potently and selectively inhibits the growth of endothelial cells (IC50 < 1 nM), impairing angiogenesis and tumor growth. This cytochalasin does not inhibit glucose transport or HIV-1 protease activity.
Use and description: scientific research reagent
Storage conditions:
15 ~ 20 ° C
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