Cytochalasin C

 

Cytochalasin C (Cytochalasin C) is a cytoosmotic actin polymeric inhibitor derived from fungal metabolites. It can enhance transcription of TGF-β1 and collagenase.

Molecular formula: C30H37NO6
Molecular weight: 507.6

Physical properties and indexes:

Appearance: …………………… White crystalline powder

Solubility: ………………… Soluble in DMSO(10mg/ml), insoluble in water.

Burning residue: ……………… < 0.1%

Purity: …………………… > 98%

Biological activity

The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such  diverse processes as cell movement, growth, phagocytosis, degranulation,  and secretion. Cytochalasin C has been shown to be 10 times less toxic in mice than the related cytochalasin D,  but with essentially the same biological effectiveness against cells in culture

Storage conditions:

15 ~ 20 ° C

Usage and Description:

Scientific research reagent

 

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