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Product Name Mouse Anti-Human IgM / Gold Chinese Name 胶体金标记的小鼠抗人IgM Alias Mouse Anti-Human IgM (Gold); Immunoglobulin M; Immunogen Species Mouse Clonality Polyclonal React Species Human, Applications IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Form Liquid Concentration 0.4 mg/ml immunogen Native Human IgM Lsotype IgG Purification affinity purified by Protein G Buffer Solution 20 mM TBS (pH=8.0) with 1% BSA and 0.03% Proclin300. Storage Store at 2-8℃ for 3-6 months. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Product Detail IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
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