Product Name	Goat Anti-Rabbit IgG H&L / AF647
Chinese Name	Alexa Fluor 647标记的羊抗兔IgG H&L
Alias	Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647); Immunoglobulin G;
	Specific References  (21)     |     SL0295G-AF647 has been referenced in 21 publications. [IF=32.086] Fei Zhu. et al. Cell Reprogramming-Inspired Dynamically Responsive Hydrogel Boosts the Induction of Pluripotency via Phase-Separated Biomolecular Condensates. ADV MATER. 2023 Mar;:2211609  ICC ;  Mouse,Human.   PubMed:36989141 [IF=17.337] Wei-Lun Pan. et al. Rapid and efficient isolation platform for plasma extracellular vesicles: EV-FISHER. J EXTRACELL VESICLES. 2022 Nov;11(11):e12281  IF ;  Human.   PubMed:36404468 [IF=16.744] Junjie Feng. et al. Rapid and efficient fluorescent aptasensor for PD-L1 positive extracellular vesicles isolation and analysis: EV-ANCHOR. CHEM ENG J. 2023 Apr;:142811  IF ;  Human.   PubMed:10.1016/j.cej.2023.142811 [IF=15.828] Yang, Yang. et al. SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK. Cell Death Differ. 2022 Jan;:1-14  IF ;  Human.   PubMed:35022571 [IF=13.281] Ximu Zhang. et al. A Bioinspired Hemostatic Powder Derived from the Skin Secretion of Andrias davidianus for Rapid Hemostasis and Intraoral Wound Healing. 2021 Nov 23  IHC ;  Rat.   PubMed:34817129 [IF=11.161] Tang, Xiaozhu. et al. A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing. J Exp Clin Canc Res. 2022 Dec;41(1):1-15  IF ;  Human.   PubMed:35260179 [IF=9.273] Canyu Yang. et al. Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin. ASIAN J PHARM SCI. 2022 Jul;:  IF ;  Human.   PubMed:10.1016/j.ajps.2022.06.002 [IF=8.947] Zhen-Han Feng. et al. A combination strategy based on an Au nanorod/doxorubicin gel via mild photothermal therapy combined with antigen-capturing liposomes and anti-PD-L1 agent promote a positive shift in the cancer-immunity cycle. Acta Biomater. 2021 Oct;:  IF ;  Mouse.   PubMed:34619371 [IF=8.679] Zhiyong Shen. et al. GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer. Cancer Lett. 2022 May;534:215617  IF ;  Human.   PubMed:35257833 [IF=8.469] Jie Jin. et al. Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting. Cell Death Dis. 2021 Jul;12(7):1-11  IF ;  Human.   PubMed:34257278 [IF=7.666] Yan Liu. et al. S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression. CELLS-BASEL. 2022 Jan;11(22):3579  IF ;  Human, Mouse.   PubMed:36429008 [IF=7.333] Li B et al. Homogenous Magneto-Fluorescent Nanosensor for Tumor-Derived Exosome Isolation and Analysis. ACS Sens. 2020 Jul 24;5(7):2052-2060.  ICF ;  Rabbit.   PubMed:32594744 [IF=6.304] Renjie Dou. et al. Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. Cell Death Dis. 2021 Feb;12(2):1-13  IF ;  Human.   PubMed:33627630 [IF=6.284] Yingchun Chen. et al. Cooperation of ATF4 and CTCF promotes adipogenesis through transcriptional regulation. 2021 May 05  IF ;  Mouse.   PubMed:33950334 [IF=5.875] Yuan SJ. et al. Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.. Int J Pharmaceut. 2021 Jul;606:120872-120872  IF ;  Mouse.   PubMed:34246743 [IF=5.285] Chaochao Luo. et al. Sodium acetate promotes fat synthesis by suppressing TATA element modulatory factor 1 in bovine mammary epithelial cells. ANIM NUTR. 2023 Jan;:  IF ;  Bovine.   PubMed:10.1016/j.aninu.2023.01.002 [IF=4.451] Yujia Jin. et al. Resveratrol exhibits inhibition effects on osteogenic differentiation of aortic valve interstitial cells by interfering with the AKT pathway. J Funct Foods. 2022 Apr;91:105002  IF ;  Pig.   PubMed:10.1016/j.jff.2022.105002 [IF=4.26] Luo et al. SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells. (2018) Sci.Rep. 8:3912  IF(ICC) ;  Rabbit.   PubMed:29500367 [IF=2.96] Iwamori T et al. Novel localizations and interactions of intercellular bridge proteins revealed by proteomic profiling. Biol Reprod. 2020 Jan 29. pii: ioaa017.  ICF&IHF ;  Rabbit.   PubMed:31995159 [IF=2.884] Zhu D et al. Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis. Mol Cell Biochem. 2019 Sep;459(1-2):141-150.  ICF ;  Rabbit.   PubMed:31297660 [IF=2.65] Li, Hongyan, et al. "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." Life Sciences 167 (2016): 57-66.  IF(IHC-P) ;  Rabbit.   PubMed:27815023
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Rabbit,
Applications	Flow-Cyt=1:100-1000 IF=1:100-1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Concentration	2.0 mg/ml
immunogen	Native rabbit IgG
Lsotype	IgG
Purification	affinity purified by Protein G, nonspecific adsorbed
Buffer Solution	10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
Storage	Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

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