Product Name	Goat Anti-Rat IgG H&L / HRP
Chinese Name	辣根过氧化物酶标记的羊抗大鼠IgG H&L
Alias	Goat Anti-Rat IgG H&L (HRP); Immunoglobulin G;
	Specific References  (19)     |     SL0293G-HRP has been referenced in 19 publications. [IF=14.026] Congcong Chen. et al. Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase. J PHARM ANAL. 2023 Apr;:  WB ;  Rat.   PubMed:10.1016/j.jpha.2023.04.016 [IF=4.051] Zhang, Yamei. et al. miR-18a-5p shuttled by mesenchymal stem cell-derived extracellular vesicles alleviates early brain injury following subarachnoid hemorrhage through blockade of the ENC1/p62 axis. CELL TISSUE RES. 2023 Feb;:1-17  WB ;  Rat.   PubMed:36795153 [IF=4.011] Wassie T et al. Recombinant B2L and Kisspeptin-54 DNA Vaccine Induces Immunity Against Orf Virus and Inhibits Spermatogenesis In Rats. Sci Rep. 2019 Nov 7;9(1):16262.  ELISA ;  Rat.   PubMed:31700161 [IF=3.947] Ma, Wenbin. et al. CircPCNX Promotes PDGF-BB-Induced Proliferation and Migration of Human Aortic Vascular Smooth Muscle Cells Through Regulating miR-1278/DNMT1 Axis. CARDIOVASC DRUG THER. 2022 Jun;:1-13  WB ;  Human.   PubMed:35670983 [IF=3.943] Quanyu Chen. et al. Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model. Int Immunopharmacol. 2021 Jan;90:107180  WB ;  Hamster, Rat.   PubMed:33221167 [IF=3.503] Zhang-Jie Yang. et al. SIRT 3 was involved in Lycium barbarum seed oil protection testis from oxidative stress: in vitro and in vivo analyses. Pharm Biol. 2021;59(1):1314-1325  WB ;  Rat.   PubMed:10.1080/13880209.2021.1961822 [IF=3.49] Hu, Yong-hua, et al. "Construction and evaluation of a live vaccine against< i> Edwardsiella tarda and< i> Vibrio harveyi: Laboratory vs. mock field trial." Vaccine 29.24 (2011): 4081-4085.  ELISA ;  Rat.   PubMed:21514342 [IF=2.96] Dang, Wei, Min Zhang, and Li Sun. "< i> Edwardsiella tarda DnaJ is a virulence-associated molecular chaperone with immunoprotective potential." Fish & shellfish immunology 31.2 (2011): 182-188.  ELISA ;  Rat.   PubMed:21601637 [IF=2.96] Sun, Yun, Chun-sheng Liu, and Li Sun. "A multivalent killed whole-cell vaccine induces effective protection against< i> Edwardsiella tarda and< i> Vibrio anguillarum." Fish & Shellfish Immunology 31.4 (2011): 595-599.  ELISA ;  Rat.   PubMed:21763772 [IF=2.86] Hou, Shuai, et al. "Mechanism of Mitochondrial Connexin43′ s Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury." International Journal of Molecular Sciences 17.5 (2016): 679.  WB ;  Rat.   PubMed:27164087 [IF=2.824] Ling Kong. et al. Tg ROP18 targets IL20RB for host-defense-related-STAT3 activation during Toxoplasma gondii infection. Parasite Vector. 2020 Dec;13(1):1-14  WB ;  Monkey.   PubMed:32767999 [IF=2.766] Sun and Sun CsBAFF, a Teleost B Cell Activating Factor, Promotes Pathogen-Induced Innate Immunity and Vaccine-Induced Adaptive Immunity. (2015) PLoS.One. 10:e0136015  IF ;  Rat.   PubMed:26295165 [IF=2.705] Suhaimi H et al. Identification of secretion domain of Neospora caninum profilin. Biochem Biophys Res Commun. 2019 Nov 14. pii: S0006-291X(19)32176-X.  WB ;  Rat.   PubMed:31735333 [IF=2.56] Wang, P. et al. "Attenuation of cytokine production of interleukine -2 and perforin in Two-way mixed lymphocyte reaction by highly efficient transduction of the recombinant adenovirus expressing ICP47 gene."Life Sci J 2013;10(3):963-969  WB ;  Rat.   PubMed:ISSN:1097-8135 [IF=2.389] Huang Weizhen. et al. LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis. ANTI-CANCER DRUG. 2022 Jul;33(6):575-586  WB ;  Human.   PubMed:35324517 [IF=1.88] Wang, Xuguang, and Zhe Chen. "MicroRNA-19a functions as an oncogenic microRNA in non-small cell lung cancer by targeting the suppressor of cytokine signaling 1 and mediating STAT3 activation." International journal of molecular medicine 35.3 (2015): 839-846.  WB ;  Rat.   PubMed:25604748 [IF=1.54] Yuan H et al. Calhex231 alleviates high glucose-induced myocardial fibrosis via inhibiting Itch-ubiquitin proteasome pathway in Vitro. Biol Pharm Bull. 2019 Jun 4.  WB ;  Rat.   PubMed:31167987 [IF=1.291] Iwaki T et al. Nanobody production can be simplified by direct secretion from Escherichia coli. Protein Expr Purif. 2020 Feb 13;170:105607.  WB ;  Rat.   PubMed:32062022 [IF=0] Wang, S. M., et al. "A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 193-204.  IHC-F ;  Rat.   PubMed:25926731
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Rat,
Applications	WB=1:1000-10000 ELISA=1:1000-10000 IHC-P=1:100-1000 IHC-F=1:100-1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Concentration	2.0 mg/ml
immunogen	Native Rat IgG
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
Storage	Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

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