Product Name	Goat Anti-Rat IgG H&L / AF488
Chinese Name	Alexa Fluor 488标记的羊抗大鼠IgG H&L
Alias	Goat Anti-Rat IgG H&L (Alexa Fluor® 488); Immunoglobulin G;
	Specific References  (11)     |     SL0293G-AF488 has been referenced in 11 publications. [IF=7.666] Yan Liu. et al. S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression. CELLS-BASEL. 2022 Jan;11(22):3579  IF ;  Human, Mouse.   PubMed:36429008 [IF=7.59] Hengxian Su. et al. Cellular energy supply in promoting vascular remodeling of small-diameter vascular grafts: preliminary study of a new strategy for vascular graft development. BIOMATER SCI-UK. 2023 Mar;:  ICC ;  Mouse.   PubMed:36928127 [IF=6.656] Ning Han. et al. Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy. PHYTOMEDICINE. 2023 Jan;:154682  FCM ;  Mouse.   PubMed:36739636 [IF=5.988] Liu-Gen Li. et al. Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage. FRONT PHARMACOL. 2022; 13: 949835  IF ;  Mouse.   PubMed:36034842 [IF=5.81] Yu TT. et al. Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.. Front Pharmacol. 2022 Mar;13:837784-837784  IF ;  Mouse.   PubMed:35308251 [IF=4.96] Nan Cheng. et al. B7-H3 augments the pro-angiogenic function of tumor-associated macrophages and acts as a novel adjuvant target for triple-negative breast cancer therapy. Biochem Pharmacol. 2021 Jan;183:114298  IF ;  Mouse.   PubMed:33153969 [IF=4.932] Ting-Ting Yu. et al. Macrophages mediated delivery of chlorin e6 and treatment of lung cancer by photodynamic reprogramming. Int Immunopharmacol. 2021 Nov;100:108164  IF ;  Mouse.   PubMed:34562845 [IF=4.575] Peng, Xin. et al. A20 attenuates pyroptosis and apoptosis in nucleus pulposus cells via promoting mitophagy and stabilizing mitochondrial dynamics. INFLAMM RES. 2022 Apr;:1-16  IF ;  Rat.   PubMed:35426501 [IF=4.148] Xin Peng. et al. The mitochondrial antioxidant SS-31 attenuated lipopolysaccharide-induced apoptosis and pyroptosis of nucleus pulposus cells via scavenging mitochondrial ROS and maintaining the stability of mitochondrial dynamics. 2021 Dec 14  IF ;  Rat.   PubMed:34903138 [IF=3.47] Zongyi Zhan. et al. Reduced Dendritic Spines in the Visual Cortex Contralateral to the Optic Nerve Crush Eye in Adult Mice. Invest Ophth Vis Sci. 2020 Aug;61(10):55-55  IHC ;  Mouse.   PubMed:32866269 [IF=2.3] Zhang, Haolong, et al. "Pleiotropic Effects of Survivin in Vascular Endothelial Cells." Microvascular Research (2016).  IF(IHC-P) ;  Rat.   PubMed:27373518
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Rat,
Applications	Flow-Cyt=1:100-1000 IF=1:100-1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Concentration	2.0 mg/ml
immunogen	Native Rat IgG
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
Storage	Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Cartpieces

• 
• 8

  8Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• G

  GDelete

• 
• +

  +Delete

• 
• 2

  2Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 7

  7Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• G

  GDelete

• 
• G

  GDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 7

  7Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• G

  GDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout