Product Name	IGFBP3
Chinese Name	胰岛素样生长因子Binding protein3Recombinant rabbit monoclonal anti
Alias	IBP3_HUMAN; Insulin-like growth factor-binding protein 3; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IBP3; BP-53;
Research Area	Tumour  Cell biology  immunology  Signal transduction  Growth factors and hormones  transcriptional regulatory factor  glycoprotein  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	R3G6
React Species	(predicted: Human, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	30-35kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IGFBP3
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. SWISS: P17936 Gene ID: 3486 Database links: Entrez Gene: 3486 Human SwissProt: P17936 Human
Product Picture	Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: Human plasma Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 32 kDa Observed MW: 26, 43 kDa Tissue: Mouse stomach Section type: Formalin-fixed & Paraffin embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:500 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to use) Counter stain: Hematoxylin (Blue) Comment: Color brown is the positive signal for SLM-60703R

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