Product Name	CD99
Chinese Name	CD99重组兔单克隆抗体
Alias	T-cell surface glycoprotein E; T cell surface glycoprotein E2 precursor; 12E7; Antigen identified by monoclonal 12E7 Y homolog; Antigen identified by monoclonal antibodies 12E7 F21 and O13; CD 99; CD99 antigen; CD99 molecule; CD99X; E2 antigen; Ewing Sarcoma; MIC 2; MIC 2X; MIC 2Y; MIC2; MIC2X; MIC2Y; Monoclonal antibody 12E7; MSK5X; Protein MIC2; Surface antigen MIC2.
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	D6E10
React Species	(predicted: Human, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	16kDa
Cellular localization	The cell membrane
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse CD99
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	PBS, Glycerol, BSA
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016] Function: Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Subunit: Homodimer. Interacts with PILRB. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Natural killer cells. Similarity: Belongs to the CD99 family. SWISS: P14209 Gene ID: 4267 Database links: Entrez Gene: 4267 Human Entrez Gene: 673094 Mouse Omim: 313470 Human SwissProt: P14209 Human SwissProt: Q8VCN6 Mouse Unigene: 653349 Human Unigene: 423040 Mouse CD99（P30/32MIC2）是一种Transmembrane protein，为MIC2基因产物。分布于lymphocyte、胸腺皮质细胞、卵巢的颗粒细胞、胰岛细胞和睾丸支持细胞。
Product Picture	Paraformaldehyde-fixed, paraffin embedded (human pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (CD99) Monoclonal Antibody, Unconjugated (SLM-60792R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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