Product Name	Gastric Mucin-6/MUC6
Chinese Name	粘蛋白6重组兔单克隆抗体
Alias	Gastric mucin 6 ； Gastric Mucin ；MUC 6 ； MUC-6 ； Muc6 ； MUC6 Fragment ； MUC6 mucin ； MUC6 mucin Fragment ； MUC6_HUMAN ； Mucin 6 ； Mucin 6 gastric ； Mucin 6 oligomeric mucus/gel forming ； Mucin glycoprotein Fragment ； Mucin-6 ； Secretory mucin MUC6 Fragment .
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	C8A2
React Species	(predicted: Human, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	257kDa
Cellular localization	Secretory protein
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MUC-6
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	PBS, Glycerol, BSA
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. [provided by RefSeq, Dec 2016] Function: May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Play an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Subcellular Location: Secreted. Tissue Specificity: Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. Post-translational modifications: O-glycosylated. Similarity: Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 TIL (trypsin inhibitory-like) domain. Contains 3 VWFD domains. SWISS: Q6W4X9 Gene ID: 4588 Database links: Entrez Gene: 4588 Human Entrez Gene: 353328 Mouse Entrez Gene: 282586 Rat Omim: 158374 Human SwissProt: Q6W4X9 Human SwissProt: Q80T03 Mouse Unigene: 528432 Human Unigene: 246621 Mouse Unigene: 92457 Rat

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