Product Name	AACT
Chinese Name	α-1抗胰糜蛋白酶/SERPINA3Recombinant rabbit monoclonal anti
Alias	AACT_HUMAN; SERPINA3; Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; Serpin A3; GIG24; GIG25; serpin family A member 3;
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	9C7
React Species	(predicted: Human, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human AACT
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	PBS, Glycerol, BSA
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	生化/生理作用： α-胰凝乳蛋白酶是丝氨酸肽酶，并且具有通过二硫键连接的三条多肽链（A 链-13 残基，B 链-131 残基和 C 链-97 残基）中包含的 241 个氨基酸残基。发现该酶的分子量为 25kDa。pI 是 8.75。它选择性地水解酪氨酸、苯丙氨酸、色氨酸和亮氨酸的 C-末端侧的肽键。Ca2+ 激活和稳定酶。该酶被二异丙基氟磷酸盐（DFP）、甲苯磺酰氟（PMSF）、N-对甲苯磺酰基-L-苯丙氨酸氯甲基酮（TPCK）、胰凝乳蛋白酶抑制剂、抑肽酶、α1-抗胰蛋白酶和 α2-巨球蛋白、10mM Cu2+ 和 Hg2+ 抑制。 一种丝氨酸蛋白酶，能将与芳香烃或其他大型疏水性侧链（Tyr、Trp、Phe、Met、Leu）结合的肽从键的羧基端水解。 单位定义： 一个单元将在 pH 7.8，25℃下，每分钟水解 1.0 μmole BTEE。

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