Product Name	IL-1 beta
Chinese Name	白介素1β/IL-1βRecombinant rabbit monoclonal anti
Alias	IL1B_HUMAN; Interleukin-1 beta; interleukin 1 beta; IL1F2; IL-1 beta; Catabolin; IL-1; IL1F2; IL1beta; IL1-BETA; IL-1beta; IL-1 Beta; IL-1β; IL1β; IL-1B; IL1B;   IL-1B; IL-1 ß; IL-1-ß; IL-1 ß;
Research Area	Cell biology  immunology  glycoprotein
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	1T3
React Species	(predicted: Human, )
Applications	WB=1:200-1000 IHC-P=1:100-500 ICC=1:50-200 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	31kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-1 beta
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS (pH7.4)with 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. SWISS: P01584 Gene ID: 3553

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