Product Name	ACKR3
Chinese Name	细胞表面Chemokine受体7Recombinant rabbit monoclonal anti
Alias	GPCR RDC1; C X C chemokine receptor type 7; Chemokine C X C motif receptor 7; Chemokine orphan receptor 1; CMKOR1; CXC R7; CXCR 7; CXCR7; G protein coupled receptor 159; G protein coupled receptor RDC1 homolog; GPR159; RDC 1; RDC1; CXCR7_HUMAN.
Research Area	Cell biology  Signal transduction  The cell membrane受体  G protein-coupled receptor
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	2G5
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	40kDa
Cellular localization	cytoplasmic The cell membrane Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ACKR3 : 300-362/362
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. GCPR RDC1 is reported to be expressed in human cell lines and in cultured vascular endothelial cells and in rodent brain, kidney, lung, heart, spleen, pancreas, small intestine, blood, colon, and blood vessels. ESTs have been isolated from human normal bone marrow, brain, breast, cartilage, embryo, eye, fetal lung/testis/B-cell, heart, heart/melanocyte/uterus, kidney, liver/spleen, nerve, placenta, and umbilical libraries as well as several human cancer libraries. SWISS: P25106 Gene ID: 57007 Database links: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. GCPR RDC1 is reported to be expressed in human cell lines and in cultured vascular endothelial cells and in rodent brain, kidney, lung, heart, spleen, pancreas, small intestine, blood, colon, and blood vessels. ESTs have been isolated from human normal bone marrow, brain, breast, cartilage, embryo, eye, fetal lung/testis/B-cell, heart, heart/melanocyte/uterus, kidney, liver/spleen, nerve, placenta, and umbilical libraries as well as several human cancer libraries.

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