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Product Name SOX11 Chinese Name 转录因子SOX-11蛋白Recombinant rabbit monoclonal anti Alias SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN. Research Area Tumour Cell biology Neurobiology Signal transduction Stem cells transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Monoclonal Clone NO. 1E8 React Species (predicted: Human, ) Applications WB=1:500-1000 IP=1:20-100 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 47kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen Recombinant human SOX11 protein (1-100aa) Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
Function:
Transcriptional activator.
Subcellular Location:
Nucleus.
Tissue Specificity:
Mainly expressed in the developing central nervous system.
Similarity:
Contains 1 HMG box DNA-binding domain.
SWISS:
P35716
Gene ID:
6664
Database links:Entrez Gene: 6664 Human
Entrez Gene: 20666 Mouse
Omim: 600898 Human
SwissProt: P35716 Human
SwissProt: Q7M6Y2 Mouse
Unigene: 432638 Human
Unigene: 41702 Mouse
Unigene: 466344 Mouse
Unigene: 162854 Rat
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