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Product Name PDCD2 Chinese Name 凋亡相关蛋白2Recombinant rabbit monoclonal anti Alias PDCD2_HUMAN; PDCD 2; Programmed cell death 2; Programmed cell death protein 2; RP 8; RP8; Zinc finger MYND domain containing protein 7; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp 8; Zinc finger protein Rp-8; Zinc finger protein Rp8; ZMYND 7; ZMYND7. Research Area Tumour Cell biology Apoptosis Cyclin transcriptional regulatory factor Immunogen Species Rabbit Clonality Monoclonal Clone NO. R5D3 React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 39kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PDCD2 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
SWISS:
Q16342
Gene ID:
5134
Database links:
Entrez Gene: 5134 Human
Entrez Gene: 18567 Mouse
SwissProt: Q16342 Human
SwissProt: P46718 Mouse
Product Picture Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: 293T, 2: HeLa, 3: NIH/3T3, 4: BRL Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 39 kDa Observed MW: 39 kDa
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