Product Name	Cdc23
Chinese Name	细胞分裂周期蛋白23Recombinant rabbit monoclonal anti
Alias	Cell division cycle protein 23 homolog; CDC23_HUMAN; APC8; CUT23; ANAPC8; Anaphase-promoting complex subunit 8 (APC8); Cyclosome subunit 8;
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	R4G5
React Species	(predicted: Human, Mouse, )
Applications	WB=1:500-2000 ICC=1:50-100 IF=1:50-100  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	69kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Cdc23
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008] SWISS: Q9UJX2 Gene ID: 8697 Database links: Entrez Gene: 8697 Human Entrez Gene: 52563 Mouse Entrez Gene: 291689 Rat SwissProt: Q9UJX2 Human SwissProt: Q8BGZ4 Mouse
Product Picture	Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: HeLa, 2: K-562, 3: Mouse lung Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 69 kDa Observed MW: 69 kDa

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