Product Name	ING1
Chinese Name	生长抑制因子1Recombinant rabbit monoclonal anti
Alias	Inhibitor of growth protein 1; ING1_HUMAN; p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a;
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	R3H8
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	47kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ING1
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Subcellular Location: Nucleus. Tissue Specificity: Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines. SWISS: Q9UK53 Gene ID: 3621 Database links: Entrez Gene: 3621 Human Entrez Gene: 26356 Mouse Entrez Gene: 306626 Rat SwissProt: Q9UK53 Human SwissProt: Q9QXV3 Mouse
Product Picture	Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: HT-29, 2: HepG2, 3: PC-12, 4: NIH/3T3 Protein loading quantity: 20 μg Exposure time: 10 s Predicted MW: 47 kDa Observed MW: 47kDa

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