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Product Name HES5 Chinese Name 发状分裂相关增强子-5Recombinant rabbit monoclonal anti Alias BHLHB38; Transcription factor HES-5; Class B basic helix-loop-helix protein 38 (bHLHb38); Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN. Research Area Signal transduction Stem cells transcriptional regulatory factor G protein-coupled receptor Immunogen Species Rabbit Clonality Monoclonal Clone NO. R4G8 React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HES5 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008]
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in fetal heart and brain tumors.
SWISS:
Q5TA89
Gene ID:
388585
Database links:Entrez Gene: 388585 Human
Entrez Gene: 15208 Mouse
SwissProt: Q5TA89 Human
SwissProt: P70120 Mouse
Product Picture Blocking buffer: 5% NFDM/TBST
Primary Ab dilution: 1:50000
Primary Ab incubation condition: 2 hours at
room temperature
Secondary Ab: Goat Anti-Rabbit IgG H&L
(HRP)
Lysate: 1: Human kidney cancer, 2: Human
liver, 3: Human lung, 4: Mouse liver, 5: Rat liver
Protein loading quantity: 20 ug
Exposure time: 60 s
Predicted MW: 18 kDa
Observed MW: 15 kDa
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