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Product Name NEUROD1 Chinese Name 神经Cell differentiation因子1Recombinant rabbit monoclonal anti Alias atonal; Neurod1 protein; basic helix loop helix transcription factor; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NeuroD1; neurogenic helix loop helix protein NEUROD; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; NEUROD; Neurogenic differentiation 1; Neurogenic differentiation factor 1; NIDDM; BHLHA3. Research Area Tumour Cardiovascular immunology Chromatin and nuclear signals Neurobiology Stem cells The new supersedes the old Epigenetics Immunogen Species Rabbit Clonality Monoclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:500-1000 IP=1:10-50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 40kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NEUROD1: 1-50/356 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]
SWISS:
Q13562
Gene ID:
4760
Database links:Entrez Gene: 4760 Human
Entrez Gene: 18012 Mouse
Omim: 601724 Human
SwissProt: Q13562 Human
SwissProt: Q60867 Mouse
Unigene: 574626 Human
Unigene: 709709 Human
Unigene: 4636 Mouse
Unigene: 44289 Rat
Product Picture Western blot analysis of NeuroD1 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (SLM-52948R, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: Human brain tissue lysate Lane 2: SH-SY5Y cell lysate
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