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Product Name Occludin Chinese Name 紧密连接蛋白单克隆抗体 Alias OCLN_HUMAN; Occludin; Ocl; BLCPMG; PPP1R115; PTORCH1; Tight junction protein occludin; Research Area Cell biology immunology transcriptional regulatory factor Cell adhesion molecule Immunogen Species Mouse Clonality Monoclonal React Species (predicted: Human, Mouse, ) Applications WB=1:200-1000 ICC=1:20-100 IF=1:20-100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 57kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Occludin Lsotype IgG Purification affinity purified by Protein A Buffer Solution PBS, Glycerol, BSA Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
SWISS:
Q16625
Gene ID:
100506658
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