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Product Name MUC16 Chinese Name 卵巢癌抗原单克隆抗体 Alias CA 125; CA-125; CA125 ovarian cancer antigen; Cancer antigen 125; FLJ14303; MUC16_HUMAN; MUC 16; Mucin 16; MUC-16; Mucin 16 cell surface associated; Mucin16; Ovarian cancer related tumor marker CA125; Ovarian carcinoma antigen CA125; Ovarian cancer-related tumor marker CA125 Research Area Tumour Signal transduction lymphocyte b-lymphocyte Cytoskeleton TumourCell biologyMaker Immunogen Species Mouse Clonality Monoclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 200kDa Cellular localization The cell membrane Secretory protein Form Liquid Concentration 1mg/ml immunogen Recombinant human MUC16 Protein: 12660-12923/14507 Lsotype IgG Purification affinity purified by Protein A Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.
SWISS:
Q8WXI7
Gene ID:
94025
Database links:
Entrez Gene: 94025 Human
SwissProt: Q8WXI7 Human
Unigene: 432676 Human
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