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Mouse Anti-MUC16 antibody
Mouse Anti-MUC16 antibody
CA 125; CA-125; CA125 ovarian cancer antigen; Cancer antigen 125; FLJ14303; MUC16_HUMAN; MUC 16; Mucin 16; MUC-16; Mucin 16 cell surface associated; Mucin16; Ovarian cancer related tumor marker CA125; Ovarian carcinoma antigen CA125; Ovarian cancer-relate
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Details

Product Name MUC16
Chinese Name 卵巢癌抗原单克隆抗体
Alias CA 125; CA-125; CA125 ovarian cancer antigen; Cancer antigen 125; FLJ14303; MUC16_HUMAN; MUC 16; Mucin 16; MUC-16; Mucin 16 cell surface associated; Mucin16; Ovarian cancer related tumor marker CA125; Ovarian carcinoma antigen CA125; Ovarian cancer-related tumor marker CA125  
Research Area Tumour  Signal transduction  lymphocyte  b-lymphocyte  Cytoskeleton  TumourCell biologyMaker  
Immunogen Species Mouse
Clonality Monoclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 200kDa
Cellular localization The cell membrane Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen Recombinant human MUC16 Protein: 12660-12923/14507 
Lsotype IgG
Purification affinity purified by Protein A
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.

SWISS:
Q8WXI7

Gene ID:
94025

Database links:

Entrez Gene: 94025 Human

SwissProt: Q8WXI7 Human

Unigene: 432676 Human





Product Picture
Sample:
Lane 1: Recombinant human MUC16 Protein, C-His-Avi (HEK293)( SL43121P)
Primary: Anti-MUC16 (SLM-43121M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 200 kDa
Observed band size: 50 kDa

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