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Rabbit Anti-SLCO2B1 antibody
Rabbit Anti-SLCO2B1 antibody
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Product Name SLCO2B1
Chinese Name 可溶性载质Transporter2B1抗体
Research Area Tumour  Cell biology  immunology  transcriptional regulatory factor  Transporter  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 77kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLCO2B1 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins.

Function:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.

SWISS:
O94956

Gene ID:
11309

Database links:

Entrez Gene: 11309 Human

Entrez Gene: 101488 Mouse

Entrez Gene: 140860 Rat

Omim: 604988 Human

SwissProt: O94956 Human

SwissProt: Q8BXB6 Mouse

SwissProt: Q9JHI3 Rat

Unigene: 7884 Human

Unigene: 11249 Mouse

Unigene: 44538 Rat



OATPRP2又称阴离子Transporter家族2B1、有机阴离子转运多肽相关蛋白2。
Product Picture
Sample:
Lane 1: Human HepG2 cell lysates
Primary: Anti-SLCO2B1 (SL25185R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 77 kDa
Observed band size: 75 kDa

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