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Product Name SLCO2B1 Chinese Name 可溶性载质Transporter2B1抗体 Research Area Tumour Cell biology immunology transcriptional regulatory factor Transporter Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 77kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLCO2B1 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins.
Function:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.
SWISS:
O94956
Gene ID:
11309
Database links:Entrez Gene: 11309 Human
Entrez Gene: 101488 Mouse
Omim: 604988 Human
SwissProt: O94956 Human
SwissProt: Q8BXB6 Mouse
Unigene: 7884 Human
Unigene: 11249 Mouse
Unigene: 44538 Rat
OATPRP2又称阴离子Transporter家族2B1、有机阴离子转运多肽相关蛋白2。Product Picture
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