Product Name	GFAP
Chinese Name	胶质纤维酸性蛋白抗体
Alias	Astrocyte Marker; FLJ45472; GFAP; Glial Fibrillary Acidic Protein; Intermediate filament protein; GFAP_HUMAN.
Research Area	Tumour  Cell biology  immunology  Neurobiology  Signal transduction  Stem cells  Cell adhesion molecule  Cell type markers  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	48kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant human GFAP protein: 1-390/432
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] SWISS: P14136 Gene ID: 2670 Database links: Entrez Gene: 281189 Cow Entrez Gene: 2670 Human Entrez Gene: 14580 Mouse Entrez Gene: 24387 Rat Omim: 137780 Human SwissProt: Q28115 Cow SwissProt: P14136 Human SwissProt: P03995 Mouse
Product Picture	Sample: Lane 1: Human U87MG cell lysates Lane 2: Human U251 cell lysates Primary: Anti-GFAP (SL42001R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kDa Observed band size: 50 kDa Measured by its binding ability in a indirect ELISA. Immobilized Human GFAP protein, His Tag (Cat. SL42001P) at 2 μg/mL (100 μL/well) can bind  Rabbit Anti-Human GFAP Antibody, the EC50 is 540.1 ng/mL.

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