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Product Name ORAI3 Chinese Name 嗅觉受体AI3抗体 Alias ORAI calcium release activated calcium modulator 3; ORAI3_HUMAN; Protein orai 3; Protein orai-3; TMEM 142C; TMEM142C; Transmembrane protein 142C. Research Area Cell biology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ORAI3 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Predicted to enable store-operated calcium channel activity. Predicted to be involved in store-operated calcium entry. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Function:
Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import.
Subunit:
Interacts with CRACR2A/EFCAB4B.
Subcellular Location:
Membrane.
Similarity:
Belongs to the Orai family.
SWISS:
Q9BRQ5
Gene ID:
93129
Database links:Entrez Gene: 93129 Human
Entrez Gene: 269999 Mouse
SwissProt: Q9BRQ5 Human
SwissProt: Q6P8G8 Mouse
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