TEL: +86 571 56623320 EMAIL: [email protected]
Product Name SLC25A23 Chinese Name 溶质载体家族25成员23抗体 Alias APC2; Calcium binding mitochondrial carrier protein SCaMC3; FLJ30339; MCSC2; MGC2615; Mitochondrial ATP Mg/Pi carrier protein 2; Mitochondrial Ca(2+) dependent solute carrier protein 2; SCAMC3; Small calcium binding mitochondrial carrier protein 3; Solute carrier family 25 member 23; Research Area Tumour Cell biology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Horse, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 52kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC25A23: 41-140/468 Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SLC25A23 is a calcium dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
Function:
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
Subcellular Location:
Mitochondrial inner membrane; Multi pass membrane protein.
Tissue Specificity:
Present in various cell lines (at protein level). Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas.
Similarity:
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Contains 3 EF-hand domains.
Contains 3 Solcar repeats.
SWISS:
Q9BV35
Gene ID:
79085
Database links:Entrez Gene: 79085 Human
Entrez Gene: 66972 Mouse
Omim: 608746 Human
SwissProt: Q9BV35 Human
SwissProt: Q6GQS1 Mouse
Product Picture Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Primary: Anti-SLC25A23 (SL21225R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 50 kDa
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC25A23) Polyclonal Antibody, Unconjugated (SL21225R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Scan Wechat Qrcode