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Product Name mouse H-2Db/PE Chinese Name PE标记小鼠H-2Db单克隆抗体 Alias HA11_MOUSE; H-2 class I histocompatibility antigen, D-B alpha chain; H-2D(B); H2-D1; H-2D; H2-D; H2-K1; Immunogen Species Mouse Clonality Monoclonal Clone NO. 2H3 React Species (predicted: Mouse, ) Applications Flow-Cyt=10ul/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 41kDa Form Liquid Lsotype Mouse IgG2a, k Purification Affinity purified by Protein G Buffer Solution 0.01M PBS, 0.5%BSA, 0.03% Proclin300 Storage Store at 2-8℃. Protect from light. Avoid freezing. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; negative regulation of neuron projection development; and positive regulation of T cell mediated cytotoxicity. Located in external side of plasma membrane. Colocalizes with membrane raft. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); eye disease (multiple); human immunodeficiency virus infectious disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C). [provided by Alliance of Genome Resources, Apr 2022]
SWISS:
P01899
Gene ID:
14964
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