Product Name	human CD13/Biotin
Chinese Name	Biotin标记人CD13单克隆抗体
Alias	ANPEN; Aminopeptidase N; Alanyl aminopeptidase; Alanyl membrane aminopeptidase; Aminopeptidase M; Aminopeptidase N; ANPEP; APN; CD 13; CD13 antigen; gp150; hAPN; Lap 1; Lap1; Alanyl (membrane) aminopeptidase; AMPN_HUMAN; AP M; AP N; AP-M; AP-N; LAP 1; LAP1; PEPN; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150.
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	13F1
React Species	(predicted: Human, )
Applications	Flow-Cyt=10ul/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	109kDa
Detection molecular weight	150-170
Form	Liquid
Lsotype	Mouse IgG2a, k
Purification	Affinity purified by Protein G
Buffer Solution	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage	Store at 2-8℃. Protect from light. Avoid freezing.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020] SWISS: P15144 Gene ID: 290

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