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Product Name mouse CD45RB/PE Chinese Name PE标记小鼠CD45RB单克隆抗体 Immunogen Species Rat Clonality Monoclonal Clone NO. 8C7 React Species (predicted: Mouse, ) Applications Flow-Cyt=10ul/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Detection molecular weight 200 Form Liquid Lsotype Rat IgG2a, κ Purification Affinity purified by Protein G Buffer Solution 0.01M PBS, 0.5%BSA, 0.03% Proclin300 Storage Store at 2-8℃. Protect from light. Avoid freezing. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
SWISS:
P06800
Gene ID:
19264
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