Product Name	mouse CD45R/B220/AF700
Chinese Name	AF700标记小鼠CD45R单克隆抗体
Immunogen Species	Rat
Clonality	Monoclonal
Clone NO.	3B6
React Species	(predicted: Mouse, )
Applications	Flow-Cyt=10ul/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Lsotype	Rat IgG2a, k
Purification	Affinity purified by Protein G
Buffer Solution	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage	Store at 2-8℃. Protect from light. Avoid freezing.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. SWISS: P06800 Gene ID: 19264

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