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Product Name Human Treg Flow Kit (FOXP3 PE/CD4 FITC/CD25 APC) Chinese Name 人Treg调节性T细胞检测试剂盒(FOXP3 PE/CD4 FITC/CD25 APC) Alias CD4+CD25+FOXP3+Treg调节性T细胞检测试剂盒; 调节性T细胞; Immunogen Species Rabbit Clonality Polyclonal Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.immunogen KLH conjugated synthetic peptide derived from human Human Treg Flow Kit (FOXP3 PE/CD4 FITC/CD25 APC) Lsotype Purification affinity purified by Protein A Storage Store at 2-8℃.Do not freeze.(12months). Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail T regulatory (Treg) cells are a subset of T lymphocytes which is characterized by CD4+ / CD25+ / FOXP3+. These naturally occurring Treg cells originate in the thymus, and comprise 2-10% of peripheral CD4+ T cells. It has been shown that Treg cells are able to inhibit T cells proliferation and cytokine production and play critical roles in preventing autoimmunity as well as in controlling tumor immunity and transplantation tolerance. Impaired Treg function or Treg cell deficiency will develop variety of autoimmune diseases, while higher frequency of Treg cells will cause hypo-immune response to pathogens.
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