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Product Name human CD105/AF488 Chinese Name AF488标记人CD105单克隆抗体 Alias END; Endoglin; ENG; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; CD 105; CD105 antigen; EGLN_HUMAN; AI528660; AI662476; S-endoglin; SN6. Immunogen Species Mouse Clonality Monoclonal Clone NO. 3C8 React Species (predicted: Human, ) Applications Flow-Cyt=10ul/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 70kDa Detection molecular weight 90 Form Liquid Lsotype Mouse IgG1, k Purification Affinity purified by Protein G Buffer Solution 0.01M PBS, 0.5%BSA, 0.03% Proclin300 Storage Store at 2-8℃. Protect from light. Avoid freezing. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
SWISS:
P17813
Gene ID:
2022
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