Product Name	human TCR γ/δ/FITC
Chinese Name	PE标记人TCR γ/δ单克隆抗体
Alias	TCR γ; TCR-γ; T cell receptor gamma; T cell receptor gamma alternate reading frame protein; T cell receptor gamma chain; T-cell receptor gamma-chain constant region; TCR gamma alternate reading frame protein; TCRG; TCRGC2; T-cell receptor gamma-2 chain C region; T-cell receptor gamma chain C region PT-gamma-1/2; TRGC2_HUMAN.
Immunogen Species
Clonality	Monoclonal
Clone NO.	5C9
React Species	(predicted: Human, )
Applications	Flow-Cyt=10ul/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Lsotype	Armenian Hamster IgG
Purification	Affinity purified by Protein G
Buffer Solution	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage	Store at 2-8℃. Protect from light. Avoid freezing.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangement of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia. [provided by RefSeq, Jul 2008] SWISS: P03986 Gene ID: 6965

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